Tag: Lambert-Eaton myasthenic syndrome

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37. Effects of various drugs on the neuromuscular junction

  1. Pyridostigmine is a reversible acetylcholinesterase inhibitor?
  2. Amifampridine blocks potassium channel efflux in nerve terminals which increases duration of the action potential?
  3. Aminoglycoside antibiotics can aggravate myasthenia gravis (MG) ?
  4. Patients with MG show decreased susceptibility to depolarizing neuromuscular blocking agents ?
  5. Patients with MG show increased susceptibility to non-depolarizing neuromuscular blocking agents?
  6. Patients with Lambert-Eaton myasthenic syndrome show decreased susceptibility to both depolarizing and non-depolarizing neuromuscular blockers?

  1. T
  2. T
  3. T
  4. T
  5. T
  6. F

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34. Diagnosis of myasthenia gravis

  1. The titer of anti-AChR antibodies in patients with myasthenia gravis (MG) closely matches the severity of symptoms?
  2. The sensitivity of anti-AChR antibodies with pure ocular MG is between 85 – 90% ?
  3. Repetitive nerve stimulation typically shows decremental response in MG?
  4. Repetitive nerve stimulation typically shows facilitation in Lambert-Eaton myasthenic syndrome?
  5. Single-fiber electromyography is the most sensitive test for MG?
  6. Subjective improvement in muscular weakness  after intravenous edrophonium is considered as positive Tensilon test and confirmation of MG ?

  1. F
  2. F
  3. T
  4. T
  5. T
  6. F